Ocular atopy and mycotic keratitis

Ann Ophthalmol. 1990 Oct;22(10):369-72.

Abstract

In a retrospective analysis, we studied the association between ocular atopy and keratomycosis. Forty-one (26.3%) of 156 patients with fungal corneal ulcers were found to have preexisting allergic conjunctivitis. All patients had been using a combination of antibiotics and corticosteroids before developing the corneal ulcer. Fungus isolation on Sabouraud's agar medium was obtained in 74.8% (31/42) ulcers. The most common fungi isolated were Fusarium (32.3%) and Aspergillus (29%). One percent silver sulfadiazine was used as an antifungal agent in these patients. Overall efficacy of this drug was found to be 77.8%, with Fusarium being the most sensitive (87.5%).

MeSH terms

  • Adolescent
  • Adrenal Cortex Hormones / therapeutic use
  • Adult
  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Child
  • Conjunctivitis, Allergic / complications*
  • Eye Infections, Fungal / drug therapy
  • Eye Infections, Fungal / etiology*
  • Eye Infections, Fungal / microbiology
  • Female
  • Fungi / drug effects
  • Fungi / isolation & purification
  • Humans
  • Keratitis / drug therapy
  • Keratitis / etiology*
  • Keratitis / microbiology
  • Male
  • Middle Aged
  • Mycoses / drug therapy
  • Mycoses / etiology*
  • Mycoses / microbiology
  • Retrospective Studies
  • Silver Sulfadiazine / therapeutic use

Substances

  • Adrenal Cortex Hormones
  • Anti-Bacterial Agents
  • Silver Sulfadiazine