Successful treatment of duodenal myeloid sarcoma with allogeneic bone marrow transplantation and additional radiotherapy

Intern Med. 2012;51(7):769-72. doi: 10.2169/internalmedicine.51.6652. Epub 2012 Apr 1.

Abstract

Myeloid sarcoma (MS) is a tumor consisting of myeloid blasts that occurs at an anatomical site other than the bone marrow. We report the case of a 38-year-old man with duodenal MS who underwent an allogeneic bone marrow transplant in a non-complete remission (CR) state. After the transplant, residual disease was suspected on a fluorodeoxyglucose positron emission tomography (FDG-PET)/CT scan, and additional radiotherapy resulted in CR, which has been maintained for 21 months. FDG-PET/CT scanning is useful for evaluating residual myeloid sarcoma during the peritransplant period.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bone Marrow Transplantation
  • Duodenal Neoplasms / diagnostic imaging
  • Duodenal Neoplasms / radiotherapy*
  • Duodenal Neoplasms / therapy*
  • Fluorodeoxyglucose F18
  • Humans
  • Male
  • Multimodal Imaging
  • Neoplasm, Residual / diagnostic imaging
  • Neoplasm, Residual / radiotherapy
  • Positron-Emission Tomography
  • Radiopharmaceuticals
  • Remission Induction
  • Sarcoma, Myeloid / diagnostic imaging
  • Sarcoma, Myeloid / radiotherapy*
  • Sarcoma, Myeloid / therapy*
  • Tomography, X-Ray Computed
  • Transplantation, Homologous

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18