Production of monoclonal antibodies against recombinant HBcAg

Tohoku J Exp Med. 1990 Jul;161(3):253-5. doi: 10.1620/tjem.161.253.

Abstract

Three monoclonal antibodies against recombinant HBcAg were obtained from hybridomas fused between mouse myeloma line NS1 and splenocytes of immunized Balb/C mice. They specifically bound to recombinant HBcAg. Subtypes of these monoclonal antibodies were IgM and IgA.

MeSH terms

  • Animals
  • Antibodies, Monoclonal / biosynthesis*
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Hepatitis B Core Antigens / genetics
  • Hepatitis B Core Antigens / immunology*
  • Hybridomas / immunology
  • Mice
  • Mice, Inbred BALB C
  • Recombinant Proteins / immunology
  • Tumor Cells, Cultured / immunology

Substances

  • Antibodies, Monoclonal
  • Hepatitis B Core Antigens
  • Recombinant Proteins