Comparative analysis of outcomes and costs following open radical cystectomy versus robot-assisted laparoscopic radical cystectomy: results from the US Nationwide Inpatient Sample

Eur Urol. 2012 Jun;61(6):1239-44. doi: 10.1016/j.eururo.2012.03.032. Epub 2012 Mar 30.

Abstract

Background: Although robot-assisted laparoscopic radical cystectomy (RARC) was first reported in 2003 and has gained popularity, comparisons with open radical cystectomy (ORC) are limited to reports from high-volume referral centers.

Objective: To compare population-based perioperative outcomes and costs of ORC and RARC.

Design, setting, and participants: A retrospective observational cohort study using the US Nationwide Inpatient Sample to characterize 2009 RARC compared with ORC use and outcomes.

Outcome measurements and statistical analysis: Propensity score methods were used to compare inpatient morbidity and mortality, lengths of stay, and costs.

Results and limitations: We identified 1444 ORCs and 224 RARCs. Women were less likely to undergo RARC than ORC (9.8% compared with 15.5%, p = 0.048), and 95.7% of RARCs and 73.9% of ORCs were performed at teaching hospitals (p<0.001). In adjusted analyses, subjects undergoing RARC compared with ORC experienced fewer inpatient complications (49.1% and 63.8%, p = 0.035) and fewer deaths (0% and 2.5%, p<0.001). RARC compared with ORC was associated with lower parenteral nutrition use (6.4% and 13.3%, p = 0.046); however, there was no difference in length of stay. RARC compared with ORC was $3797 more costly (p = 0.023). Limitations include retrospective design, absence of tumor characteristics, and lack of outcomes beyond hospital discharge.

Conclusions: RARC is associated with lower parenteral nutrition use and fewer inpatient complications and deaths. However, lengths of stay are similar, and the robotic approach is significantly more costly.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Aged
  • Chi-Square Distribution
  • Cost-Benefit Analysis
  • Cystectomy / adverse effects
  • Cystectomy / economics*
  • Cystectomy / methods
  • Cystectomy / mortality
  • Databases, Factual
  • Female
  • Hospital Costs*
  • Hospitals, Teaching / economics
  • Humans
  • Inpatients*
  • Laparoscopy / adverse effects
  • Laparoscopy / economics*
  • Laparoscopy / mortality
  • Length of Stay / economics
  • Logistic Models
  • Male
  • Models, Economic
  • Outcome and Process Assessment, Health Care / economics*
  • Parenteral Nutrition / economics
  • Postoperative Complications / economics
  • Postoperative Complications / etiology
  • Postoperative Complications / therapy
  • Propensity Score
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors
  • Robotics / economics*
  • Surgery, Computer-Assisted / adverse effects
  • Surgery, Computer-Assisted / economics*
  • Surgery, Computer-Assisted / mortality
  • Time Factors
  • Treatment Outcome
  • United States
  • Urinary Bladder Neoplasms / economics*
  • Urinary Bladder Neoplasms / mortality
  • Urinary Bladder Neoplasms / pathology
  • Urinary Bladder Neoplasms / surgery*