Identification of a novel HLA-A*23 variant allele, A*23:50

Tissue Antigens. 2012 May;79(5):386. doi: 10.1111/j.1399-0039.2012.01860.x.

Abstract

HLA-A*23:50 differs from HLA-A*23:01:01 by one nucleotide at position 112 resulting in an amino acid change, Arginine to Tryptophan, at codon 14 of exon 2.

Publication types

  • Case Reports

MeSH terms

  • Alleles*
  • Amino Acid Substitution
  • Arginine / genetics
  • Black or African American
  • Bone Marrow Transplantation
  • Codon
  • DNA Fingerprinting
  • Exons
  • HLA-A Antigens / genetics*
  • HLA-A Antigens / immunology
  • Histocompatibility Testing
  • Humans
  • Polymorphism, Single Nucleotide
  • Sequence Analysis, DNA
  • Tryptophan / genetics
  • United States

Substances

  • Codon
  • HLA-A Antigens
  • HLA-A*23 antigen
  • Tryptophan
  • Arginine