Fast automated NMR spectroscopy of short-lived biological samples

Suhas Tikole; Victor Jaravine; Vladimir V Rogov; Alexis Rozenknop; Kerstin Schmöe; Frank Löhr; Volker Dötsch; Peter Güntert

doi:10.1002/cbic.201200044

Fast automated NMR spectroscopy of short-lived biological samples

Chembiochem. 2012 May 7;13(7):964-7. doi: 10.1002/cbic.201200044. Epub 2012 Apr 11.

Authors

Suhas Tikole¹, Victor Jaravine, Vladimir V Rogov, Alexis Rozenknop, Kerstin Schmöe, Frank Löhr, Volker Dötsch, Peter Güntert

Affiliation

¹ Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance, Goethe University Frankfurt, Max-von-Laue-Strasse 9, 60438 Frankfurt am Main, Germany.

PMID: 22492650
DOI: 10.1002/cbic.201200044

Abstract

Faster than death: NMR techniques that make use of nonlinear sampling and hyperdimensional processing enable the recording of complete NMR data sets for the automated assignment of the backbone and side-chain resonances of short-lived protein samples of cell lysates.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biomedical Research
Nuclear Magnetic Resonance, Biomolecular / methods*
Proteins / chemistry*

Substances

Proteins