Abstract
The Roche LightCycler mycobacterium detection molecular assay for Mycobacterium tuberculosis, M. avium, and M. kansasii, was applied to tissue specimens. It performed well on lymph node and cerebrospinal fluid specimens and less well on lung, liver, and bone marrow core biopsy specimens, but used in conjunction with a clinical suspicion of tuberculosis, it could augment patient management.
Publication types
-
Evaluation Study
-
Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
-
Adult
-
Aged
-
Aged, 80 and over
-
Bacteriological Techniques / methods*
-
Bone Marrow / microbiology
-
Cerebrospinal Fluid / microbiology
-
Female
-
Humans
-
Liver / microbiology
-
Lung / microbiology
-
Lymph Nodes / microbiology
-
Male
-
Middle Aged
-
Molecular Diagnostic Techniques / methods*
-
Mycobacterium tuberculosis / genetics
-
Mycobacterium tuberculosis / isolation & purification*
-
Real-Time Polymerase Chain Reaction / methods*
-
Tuberculosis / diagnosis*
-
Tuberculosis / microbiology*