A new "turn-on" chemodosimeter for Hg2+: ICT fluorophore formation via Hg(2+)-induced carbaldehyde recovery from 1,3-dithiane

Yuncong Chen; Chengcheng Zhu; Zhenghao Yang; Jing Li; Yang Jiao; Weijiang He; Junjie Chen; Zijian Guo

doi:10.1039/c2cc31217d

A new "turn-on" chemodosimeter for Hg2+: ICT fluorophore formation via Hg(2+)-induced carbaldehyde recovery from 1,3-dithiane

Chem Commun (Camb). 2012 May 25;48(42):5094-6. doi: 10.1039/c2cc31217d. Epub 2012 Apr 18.

Authors

Yuncong Chen¹, Chengcheng Zhu, Zhenghao Yang, Jing Li, Yang Jiao, Weijiang He, Junjie Chen, Zijian Guo

Affiliation

¹ State Key Laboratory of Coordination Chemistry, Coordination Chemistry Institute, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, PR China.

PMID: 22514021
DOI: 10.1039/c2cc31217d

Abstract

A novel sensitive and specific Hg(2+) chemodosimeter, derived from 1',3'-dithiane-substituted 2,1,3-benzoxadiazole, displays "turn-on" fluorescent and colorimetric responses via an Hg(2+)-triggered aldehyde recovery reaction. Its potential to monitor Hg(2+) in living organisms has been demonstrated using zebrafish larvae.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aldehydes / chemistry
Animals
Benzoxazoles / chemistry
Colorimetry
Fluorescent Dyes / chemistry
Heterocyclic Compounds / chemistry*
Ions / chemistry
Larva / metabolism
Mercury / chemistry*
Zebrafish / growth & development

Substances

Aldehydes
Benzoxazoles
Fluorescent Dyes
Heterocyclic Compounds
Ions
1,3-dithiane
Mercury