Pattern recognition receptors in infectious skin diseases

Heleen D de Koning; Anna Simon; Patrick L J M Zeeuwen; Joost Schalkwijk

doi:10.1016/j.micinf.2012.03.004

Pattern recognition receptors in infectious skin diseases

Microbes Infect. 2012 Sep;14(11):881-93. doi: 10.1016/j.micinf.2012.03.004. Epub 2012 Mar 31.

Authors

Heleen D de Koning¹, Anna Simon, Patrick L J M Zeeuwen, Joost Schalkwijk

Affiliation

¹ Department of Dermatology, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB, The Netherlands. [email protected]

PMID: 22516809
DOI: 10.1016/j.micinf.2012.03.004

Abstract

During the last decade, multiple pattern recognition receptors (PRRs) have been identified. These are involved in the innate immune response against a plethora of pathogens. However, PRR functioning can also be detrimental, even during infections. This review discusses the current knowledge on PRRs that recognize dermatotropic pathogens, and potential therapeutical implications.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Host-Pathogen Interactions
Humans
Immunity, Innate
Receptors, Pattern Recognition / immunology*
Skin Diseases, Infectious / immunology*

Substances

Receptors, Pattern Recognition