Mortality and its predictors in severe bulimia nervosa patients

Eur Eat Disord Rev. 2013 Jan;21(1):15-9. doi: 10.1002/erv.2178. Epub 2012 Apr 23.

Abstract

Background: The risk of mortality remains unclear for bulimia nervosa (BN) patients, especially the most severe. The aims of this study were to improve knowledge on BN and mortality.

Methods: With initial evaluation at admission, 258 BN (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition) consecutive inpatients were included (1988-2004). Vital status was established from the French national register. Standardized Mortality Ratio (SMR) calculation and bivariate Cox analysis were performed for the hypothesised predictors of mortality.

Results: Mean follow-up duration was 10.5 years. Ten deaths were recorded, and the crude mortality ratio was 3.9%; SMR = 5.52 [CI95 (2.64-10.15)]. The majority of deaths were from suicide [6/10, SMR = 30.9 (5.7-68.7)]. The mean age at time of death was 29.6 years. Predictive factors were previous suicide attempt and low minimum BMI.

Conclusions: Severe BN patients are at higher risk of death (mainly suicide) especially if previous suicide attempt or previous low BMI. More studies are needed to confirm these results.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Body Mass Index
  • Bulimia Nervosa / mortality*
  • Cause of Death
  • Cohort Studies
  • Female
  • Follow-Up Studies
  • France / epidemiology
  • Humans
  • Middle Aged
  • Prospective Studies
  • Risk Factors
  • Suicide / statistics & numerical data*
  • Suicide, Attempted / statistics & numerical data*
  • Young Adult