Pain ratings by patients and their providers of radionucleotide injection for breast cancer lymphatic mapping

Pain Med. 2012 May;13(5):670-6. doi: 10.1111/j.1526-4637.2012.01374.x. Epub 2012 Apr 26.

Abstract

Background: Disparity between patient report and physician perception of pain from radiotracer injection for sentinel node biopsy is thought to center on the severity of the intervention, ethnic composition of population queried, and socioeconomic factors.

Objective: The objectives of this study were, first, to explore agreement between physicians' and their breast cancer patients' pain assessment during subareolar radionucleotide injection; and second, to evaluate potential ethnic differences in ratings.

Methods: A trial was conducted, from January 2006 to April 2009, where 140 breast cancer patients were randomly assigned to standard topical lidocaine-4% cream and 99mTc-sulfur colloid injection, or to one of three other groups: placebo cream and 99mTc-sulfur colloid injection containing NaHCO3, 1% lidocaine, or NaHCO3 + 1% lidocaine. Providers and patients completed numeric pain scales (0-10) immediately after injection.

Results: Patients and providers rated pain similarly over the entire cohort (median, 3 vs 2, P = 0.15). Patients rated pain statistically significantly higher than physicians in the standard (6 vs 5, P = 0.045) and placebo + NaHCO3 (5 vs 4, P = 0.032) groups. No significant difference in scores existed between all African Americans and their physicians (3 vs 4, P = 0.27).

Conclusion: Patient-physician pain assessment congruence over the less painful injections and their statistically similar scores with the more painful methods suggests the importance of utilizing the least painful method possible. Providers tended to underestimate patients with the highest pain ratings-those in the greatest analgesic need. Lack of statistical difference between African American and physician scores may reflect the equal-access-to-care over the entire patient cohort, supporting the conclusion that socioeconomic factors may lie at the heart of previously reported discrepancies.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Breast Neoplasms / complications
  • Breast Neoplasms / diagnostic imaging
  • Breast Neoplasms / pathology*
  • Cohort Studies
  • Female
  • Humans
  • Injections
  • Lidocaine / administration & dosage
  • Lidocaine / adverse effects
  • Lymph Nodes / diagnostic imaging*
  • Middle Aged
  • Pain / etiology
  • Pain / physiopathology*
  • Pain Measurement
  • Patients / statistics & numerical data*
  • Physicians / statistics & numerical data*
  • Radionuclide Imaging
  • Radiopharmaceuticals* / administration & dosage
  • Rhenium* / administration & dosage
  • Technetium Tc 99m Sulfur Colloid* / administration & dosage

Substances

  • Radiopharmaceuticals
  • technetium Tc rhenium-sulfur colloid
  • Technetium Tc 99m Sulfur Colloid
  • Rhenium
  • Lidocaine