Evidence for lack of acquisition of tolerance in Salmonella enterica serovar Typhimurium ATCC 14028 after exposure to subinhibitory amounts of Origanum vulgare L. essential oil and carvacrol

Isabelle da Silva Luz; Nelson Justino Gomes Neto; Adassa Gama Tavares; Pollyana Campos Nunes; Marciane Magnani; Evandro Leite de Souza

doi:10.1128/AEM.00605-12

Evidence for lack of acquisition of tolerance in Salmonella enterica serovar Typhimurium ATCC 14028 after exposure to subinhibitory amounts of Origanum vulgare L. essential oil and carvacrol

Appl Environ Microbiol. 2012 Jul;78(14):5021-4. doi: 10.1128/AEM.00605-12. Epub 2012 Apr 27.

Authors

Isabelle da Silva Luz¹, Nelson Justino Gomes Neto, Adassa Gama Tavares, Pollyana Campos Nunes, Marciane Magnani, Evandro Leite de Souza

Affiliation

¹ Laboratory of Food Microbiology, Department of Nutrition, Health Sciences Center, Federal University of Paraíba, João Pessoa, Brazil.

Abstract

Overnight exposure of Salmonella enterica serovar Typhimurium to sublethal amounts of Origanum vulgare essential oil (OV) and carvacrol (CAR) did not result in direct and cross-bacterial protection. Cells subcultured with increasing amounts of OV or CAR survived up to the MIC of either compound, revealing few significant changes in bacterial susceptibility.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / pharmacology*
Cross Protection
Culture Media
Cymenes
Humans
Microbial Sensitivity Tests
Microbial Viability
Monoterpenes / pharmacology*
Oils, Volatile / pharmacology*
Origanum / metabolism*
Salmonella typhimurium / drug effects*
Salmonella typhimurium / growth & development*
Time Factors

Substances

Anti-Bacterial Agents
Culture Media
Cymenes
Monoterpenes
Oils, Volatile
origanum oil
carvacrol