Engineered arterial models to correlate blood flow to tissue biological response

Ann N Y Acad Sci. 2012 Apr;1254(1):51-56. doi: 10.1111/j.1749-6632.2012.06518.x.

Abstract

This paper reviews how biomedical engineers, in collaboration with physicians, biologists, chemists, physicists, and mathematicians, have developed models to explain how the impact of vascular interventions on blood flow predicts subsequent vascular repair. These models have become increasingly sophisticated and precise, propelling us toward optimization of cardiovascular therapeutics in general and personalizing treatments for patients with cardiovascular disease.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Arteries / physiology*
  • Biocompatible Materials
  • Biomedical Engineering
  • Blood Flow Velocity / physiology
  • Blood Vessel Prosthesis
  • Cardiovascular Diseases / physiopathology
  • Cardiovascular Diseases / therapy
  • Humans
  • Models, Cardiovascular*

Substances

  • Biocompatible Materials