Abstract
We describe the case of a serological reactivation in a Toxoplasma-seropositive subject, following a cardiac transplantation transmitting cysts contained in the myocardial tissue. In a context of acute graft rejection, primary chemoprophylaxis enables to avoid onset of opportunistic toxoplasmosis, emerging with immunodepletion performed by high-dose steroids. Then, we draw up a brief review of the bibliographical literature about pathophysiological mechanisms of toxoplasmic reactivation in heart transplants.
Publication types
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Case Reports
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English Abstract
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Review
MeSH terms
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Acute Disease
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Antibodies, Protozoan / blood
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Antibodies, Protozoan / immunology*
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Graft Rejection / etiology*
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Graft Rejection / immunology
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Graft Rejection / parasitology
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Heart Transplantation / adverse effects*
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Heart Transplantation / immunology*
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Heart Transplantation / physiology
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Humans
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Lymphocyte Activation / immunology
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Lymphocyte Activation / physiology
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Male
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Middle Aged
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Serology
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Tissue Donors
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Toxoplasma / immunology
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Toxoplasma / isolation & purification
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Toxoplasma / physiology
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Toxoplasmosis / blood
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Toxoplasmosis / diagnosis*
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Toxoplasmosis / etiology*
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Toxoplasmosis / immunology