[Ocular toxoplasmosis in AIDS]

Ann Med Interne (Paris). 1990;141(5):472-4.
[Article in French]

Abstract

Since 1983, we have seen 11 cases of toxoplasmic retinochoroiditis in patients with AIDS. Ocular toxoplasmosis appears to be a growing concern in AIDS: 3.3% in 1983, 6.1% in 1988 and 5.9% during the first trimester of 1989. Anti-Toxoplasma gondii antibody titers in the aqueous humour were not conclusive, therefore the diagnosis was based on ophthalmoscopic criteria and on a rapid response to specific therapy. As for brain toxoplasmosis, treatment must be continued indefinitely to prevent relapse. Seven out of 11 patients had cerebral toxoplasmosis, which was diagnosed by computerized tomography (CT) scan. This suggests that a neurological evaluation and a brain CT scan should be performed in all AIDS patients with toxoplasmic retinochoroiditis.

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications*
  • Adult
  • Brain Diseases / diagnostic imaging
  • Brain Diseases / etiology
  • Humans
  • Male
  • Middle Aged
  • Opportunistic Infections / drug therapy
  • Opportunistic Infections / epidemiology
  • Opportunistic Infections / etiology*
  • Pyrimethamine / therapeutic use
  • Retrospective Studies
  • Sulfadiazine / therapeutic use
  • Tomography, X-Ray Computed
  • Toxoplasmosis / etiology
  • Toxoplasmosis, Ocular / drug therapy
  • Toxoplasmosis, Ocular / epidemiology
  • Toxoplasmosis, Ocular / etiology*

Substances

  • Sulfadiazine
  • Pyrimethamine