Secretory products of macrophages: twenty-five years on

J Clin Invest. 2012 Apr;122(4):1189-90. doi: 10.1172/jci62930.

Abstract

No longer do scientists look down on macrophages as "garbage men" that act "nonspecifically." Last fall's Nobel Prizes honored two of the few scientists who studied macrophages three decades ago. Now perhaps thousands do, and the subtypes they describe reflect ongoing discoveries of macrophages' extraordinary plasticity.

Publication types

  • Autobiography
  • Biography
  • Historical Article
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Allergy and Immunology / history*
  • Animals
  • Biomedical Research*
  • Cysteine / chemistry
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Immunity, Innate
  • Interdisciplinary Communication
  • Macrophage Activation
  • Macrophages / classification
  • Macrophages / metabolism*
  • Models, Immunological
  • New York
  • Nobel Prize
  • Periodicals as Topic / history*
  • Reactive Nitrogen Species / immunology
  • Reactive Oxygen Species / immunology
  • Substrate Specificity

Substances

  • Reactive Nitrogen Species
  • Reactive Oxygen Species
  • Cysteine

Personal name as subject

  • Carl Nathan