Abstract
We report the first case of spontaneous intrapartum Atopobium vaginae bacteremia identified by 16S rRNA gene sequencing. The bacterium was misidentified by RapID ANA II, API Rapid ID 32A, and matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). The likely source of bacteremia was the female genital tract. In invasive infections caused by A. vaginae, β-lactams and clindamycin are the antibiotics of choice, as most strains are resistant to metronidazole.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Actinobacteria / classification
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Actinobacteria / genetics
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Actinobacteria / isolation & purification*
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Adult
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Anti-Bacterial Agents / therapeutic use
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Bacteremia / diagnosis*
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Bacteremia / microbiology
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Bacteremia / pathology
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Clindamycin / therapeutic use
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DNA, Bacterial / chemistry
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DNA, Bacterial / genetics
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DNA, Ribosomal / chemistry
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DNA, Ribosomal / genetics
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Drug Resistance, Bacterial
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Female
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Gram-Positive Bacterial Infections / diagnosis*
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Gram-Positive Bacterial Infections / microbiology
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Gram-Positive Bacterial Infections / pathology
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Humans
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Molecular Sequence Data
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Pregnancy
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Pregnancy Complications, Infectious / diagnosis*
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Pregnancy Complications, Infectious / microbiology
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Pregnancy Complications, Infectious / pathology
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RNA, Ribosomal, 16S / genetics
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Sequence Analysis, DNA
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beta-Lactams / therapeutic use
Substances
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Anti-Bacterial Agents
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DNA, Bacterial
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DNA, Ribosomal
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RNA, Ribosomal, 16S
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beta-Lactams
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Clindamycin