[Quality of life and adherence to nebulised antibiotic therapy using a new device in non-cystic fibrosis bronchiectasis]

Enferm Clin. 2012 May-Jun;22(3):148-53. doi: 10.1016/j.enfcli.2012.04.005. Epub 2012 May 11.
[Article in Spanish]

Abstract

Aims: Analysis of psychological variables, quality of life, depression and anxiety, subjective perception of compliance, level of satisfaction with the electronic device, and objective verification) in order to study the therapeutic adherence, in non-cystic fibrosis bronchiectasis (NCFB) colonized by Pseudomonas aeruginosa.

Methods: A cross-sectional descriptive study was conducted on 22 NCFB stable patients colonised by Pseudomonas aeruginosa (two groups of 11 subjects: GROUP 1, Pari-LC plus nebuliser device, and GROUP 2, with the I- neb device), both containing sodium colistemethate. Different variables, were obtained, such as, self-perceived health (St George questionnaire), state of mind (HADS scale), and subjective perception of therapeutic compliance and objective verification by using the device software.

Results: There were no significant differences in questionnaire results. The therapeutic support in GROUP 2, could be proved objectively (up to 60%) using specific software, and the excellent tolerability using a specific questionnaire created for the study.

Conclusions: These types of aerosol devices demonstrate a high level of therapeutic support, that can be measured objectively and is different from what the patients subjectively indicates.

MeSH terms

  • Administration, Inhalation
  • Aged
  • Anti-Bacterial Agents / administration & dosage*
  • Bronchiectasis / complications*
  • Cross-Sectional Studies
  • Cystic Fibrosis / complications*
  • Female
  • Humans
  • Male
  • Medication Adherence / statistics & numerical data*
  • Nebulizers and Vaporizers*
  • Pseudomonas Infections / drug therapy*
  • Pseudomonas Infections / etiology*
  • Pseudomonas aeruginosa*
  • Quality of Life*
  • Surveys and Questionnaires

Substances

  • Anti-Bacterial Agents