Enhanced depth imaging optical coherence tomography: choroidal thickness and correlations with age, refractive error, and axial length

Ophthalmic Surg Lasers Imaging. 2012 Jul 1;43(4):296-301. doi: 10.3928/15428877-20120426-02. Epub 2012 May 3.

Abstract

Background and objective: To evaluate choroidal thickness at five macular locations and assess the correlations between choroidal thickness at these locations with age, refractive error, and axial length.

Patients and methods: Eighty-four eyes from 42 healthy adult volunteers were included. Enhanced depth imaging by spectral-domain optical coherence tomography was performed, and choroidal thickness was measured at five macular locations: subfoveal and 3 mm nasal, temporal, superior, and inferior. Correlations of choroidal thickness at each location with age, refractive error, and axial length were analyzed.

Results: Mean choroidal thicknesses at the subfoveal, superior, inferior, temporal, and nasal locations were 293, 308, 264, 263, and 174 μm, respectively. A correlation was found between choroidal thickness, age, refractive error, and axial length at all locations.

Conclusion: Mean subfoveal choroidal thickness in healthy adults is approximately 300 μm. A correlation was found between choroidal thickness and all parameters studied.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Aging / physiology*
  • Axial Length, Eye / physiopathology*
  • Choroid / anatomy & histology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myopia / physiopathology*
  • Organ Size
  • Tomography, Optical Coherence*
  • Visual Acuity / physiology
  • Young Adult