In the mol-ecule of the title compound, C(19)H(17)NO(3)S, the dihedral angle formed by the quinoline ring system and the thio-phene ring is 83.15 (8)°. In the crystal, C-H⋯O hydrogen bonds link the mol-ecules into a C(8) chain running along the b axis. The packing of the mol-ecules is further influenced by C-H⋯π inter-actions.