[Molecular aspects of allergy to plant products. Part I. Class I and II allergens and crossreactivity of IgE antibodies]

Pol Merkur Lekarski. 2012 Feb;32(188):129-34.
[Article in Polish]

Abstract

Food allergies are adverse immunologic reactions that might be due to IgE--or none IgE-mediated immune mechanisms or mixed. One of the more common and typically most mild forms of IgE- mediated food allergy is the so-called oral allergy syndrome (OAS), although systemic symptoms after ingesting a particular fruit or vegetable can occur. Pollen food syndrome is the most common food allergy in adolescents and adults. It develops as a consequence of shared epitopes in the primary and tertiary structures of pollen and food allergens. The authors describe class I and class II allergens, as well as molecularly determined IgE-crossreactivity phenomenon. Also the problem of symptom-free consumed pollen-related food allergens, which might cause T cell-mediated late-phase skin reactions in patients with pollen allergy and atopic dermatitis, is taken up.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Adolescent
  • Adult
  • Allergens / classification
  • Allergens / immunology*
  • Antigens, Plant / immunology
  • Cross Reactions / immunology
  • Dermatitis, Atopic / immunology
  • Food Hypersensitivity / immunology*
  • Histocompatibility Antigens Class I / immunology
  • Histocompatibility Antigens Class II / immunology
  • Humans
  • Immunoglobulin E / immunology*
  • Malus / immunology
  • Plant Proteins / immunology
  • Rhinitis, Allergic, Seasonal / immunology
  • Young Adult

Substances

  • Allergens
  • Antigens, Plant
  • Histocompatibility Antigens Class I
  • Histocompatibility Antigens Class II
  • Plant Proteins
  • Immunoglobulin E