Solution NMR structure of Alr2454 from Nostoc sp. PCC 7120, the first structural representative of Pfam domain family PF11267

J Struct Funct Genomics. 2012 Sep;13(3):171-6. doi: 10.1007/s10969-012-9135-5. Epub 2012 May 17.

Abstract

Protein domain family PF11267 (DUF3067) is a family of proteins of unknown function found in both bacteria and eukaryotes. Here we present the solution NMR structure of the 102-residue Alr2454 protein from Nostoc sp. PCC 7120, which constitutes the first structural representative from this conserved protein domain family. The structure of Nostoc sp. Alr2454 adopts a novel protein fold.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Amino Acid Sequence
  • Bacterial Proteins / chemistry*
  • Bacterial Proteins / genetics
  • Cloning, Molecular
  • Escherichia coli / chemistry
  • Escherichia coli / genetics
  • Genes, Bacterial
  • Magnetic Resonance Spectroscopy / methods*
  • Molecular Sequence Data
  • Nostoc / chemistry*
  • Nostoc / genetics
  • Protein Conformation
  • Protein Folding
  • Protein Structure, Tertiary
  • Sequence Alignment
  • Solutions / chemistry

Substances

  • Bacterial Proteins
  • Solutions