Molecular evidence of St. Louis encephalitis virus infection in patients in Buenos Aires, Argentina

Laura E Valinotto; Paola R Barrero; Mariana Viegas; María C Alvarez López; Alicia S Mistchenko

doi:10.1016/j.jcv.2012.04.005

Molecular evidence of St. Louis encephalitis virus infection in patients in Buenos Aires, Argentina

J Clin Virol. 2012 Aug;54(4):349-51. doi: 10.1016/j.jcv.2012.04.005. Epub 2012 May 19.

Authors

Laura E Valinotto¹, Paola R Barrero, Mariana Viegas, María C Alvarez López, Alicia S Mistchenko

Affiliation

¹ Hospital de Niños R. Gutiérrez, Laboratorio de Virología, Gallo 1330, 1425 Buenos Aires, Argentina. [email protected]

PMID: 22608840
DOI: 10.1016/j.jcv.2012.04.005

Abstract

We report two cases of St. Louis encephalitis where the virus was detected in patients' sera directly by molecular techniques allowing subsequent typing. Phylogenetic analysis of both samples showed that NS5 sequences clustered with viruses previously classified as genotype III.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Argentina
Encephalitis Virus, St. Louis / classification*
Encephalitis Virus, St. Louis / genetics*
Encephalitis, St. Louis / blood
Encephalitis, St. Louis / diagnosis*
Encephalitis, St. Louis / virology
Female
Genotype
Humans
Middle Aged
Phylogeny
RNA, Viral / blood*
Sequence Analysis, DNA
Viral Nonstructural Proteins / genetics

Substances

NS5 protein, flavivirus
RNA, Viral
Viral Nonstructural Proteins