Occurrence and antimicrobial susceptibility of Porphyromonas spp. and Fusobacterium spp. in dogs with and without periodontitis

Anaerobe. 2012 Aug;18(4):381-5. doi: 10.1016/j.anaerobe.2012.04.008. Epub 2012 May 17.

Abstract

The occurrence of Porphyromonas gulae, Porphyromonas macacae, Fusobacterium nucleatum and Fusobacterium canifelinum in subgingival plaque from dogs with and without periodontitis as well as their antimicrobial susceptibility were evaluated. From 50 dogs with periodontitis were identified 38 P. gulae, 8 P. macacae, 26 F. nucleatum and 15 F. canifelinum, and from 50 dogs without periodontitis were identified 15 P. gulae, 12 F. nucleatum and 11 F. canifelinum. All strains were susceptible to most of the antibiotics tested, however, different resistance rates to clarithromycin, erythromycin and metronidazole among strains were observed. The role of P. gulae, P. macacae, F. nucleatum and F. canifelinum in periodontal disease of household pets needs to be defined to a better prevention and treatment of the canine periodontitis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Bacterial Agents / pharmacology
  • Bacteroidaceae Infections / microbiology
  • Clarithromycin / pharmacology
  • Dental Plaque / microbiology
  • Dog Diseases / microbiology*
  • Dogs / microbiology*
  • Drug Resistance, Bacterial
  • Erythromycin / pharmacology
  • Female
  • Fusobacterium / drug effects*
  • Fusobacterium / isolation & purification*
  • Fusobacterium / metabolism
  • Fusobacterium Infections / microbiology
  • Hemagglutination Inhibition Tests
  • Humans
  • Male
  • Metronidazole / pharmacology
  • Microbial Sensitivity Tests
  • Periodontitis / microbiology*
  • Porphyromonas / drug effects*
  • Porphyromonas / isolation & purification*
  • Porphyromonas / metabolism

Substances

  • Anti-Bacterial Agents
  • Metronidazole
  • Erythromycin
  • Clarithromycin