Irreversible protein kinase inhibitors: balancing the benefits and risks

J Med Chem. 2012 Jul 26;55(14):6243-62. doi: 10.1021/jm3003203. Epub 2012 Jun 8.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Line
  • Humans
  • Protein Kinase Inhibitors / chemistry
  • Protein Kinase Inhibitors / metabolism
  • Protein Kinase Inhibitors / pharmacology*
  • Protein Kinase Inhibitors / therapeutic use
  • Protein Kinases / chemistry
  • Protein Kinases / metabolism*
  • Risk
  • Structure-Activity Relationship
  • Time Factors

Substances

  • Protein Kinase Inhibitors
  • Protein Kinases