Validation of intracerebral hemorrhage-specific intensity of care quality metrics

J Stroke Cerebrovasc Dis. 2013 Jul;22(5):661-7. doi: 10.1016/j.jstrokecerebrovasdis.2012.03.015. Epub 2012 May 25.

Abstract

Background: Given the considerable variation in care of patients with intracerebral hemorrhage (ICH) among centers that results in differences in outcome among these patients, a new intensity of care quality metrics has been proposed. This study aimed to validate the new ICH-specific intensity of care quality metrics.

Methods: A total of 50 consecutive patients with ICH who were admitted within 24 hours of symptom onset were identified. Twenty-six quality indicators related to 18 facets of care were incorporated into a metric providing the variable, definition of the variable, and quality parameter. A score of 1 point was assigned if the quality parameter met the threshold for appropriate performance or if the parameter was not applicable, creating a total score of up to 26 points. The predictive validity of the classification scheme was tested by using the bootstrap method.

Results: Fourteen of the 50 patients with ICH died during hospitalization (28%). The intensity of care quality metric score ranged from 17 points to 26 points. The mean score was higher in those who survived compared with those who died (23 ± 3 vs 21 ± 2; P = .02). Survival increased with tertile based on higher scores (100%, 67%, and 55%; P = .017). The receiver operating characteristic curve demonstrated a high discriminating ability of intensity of care quality metrics for in-hospital mortality (0.730, 95% confidence interval, 0.591-0.869) and a C-statistic of 0.91 (95% confidence interval, 0.90-0.92).

Conclusions: Correlation of the new ICH-specific intensity of care quality metric with in-hospital mortality supports its broader use for improving and standardizing medical care among patients with ICH.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cerebral Hemorrhage / diagnosis
  • Cerebral Hemorrhage / mortality
  • Cerebral Hemorrhage / therapy*
  • Chi-Square Distribution
  • Critical Care / standards*
  • Delivery of Health Care / standards*
  • Discriminant Analysis
  • Female
  • Hospital Mortality
  • Hospitalization
  • Humans
  • Intensive Care Units / standards
  • Logistic Models
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Observer Variation
  • Quality Indicators, Health Care / standards*
  • ROC Curve
  • Reproducibility of Results
  • Survival Analysis
  • Time Factors
  • Treatment Outcome