[New painkillers inhibiting the physiological breakdown of endogenous opioids]

Med Sci (Paris). 2012 May;28(5):476-8. doi: 10.1051/medsci/2012285011. Epub 2012 May 30.
[Article in French]
No abstract available

Publication types

  • News

MeSH terms

  • Analgesia / methods
  • Analgesia / trends
  • Analgesics / adverse effects
  • Analgesics / pharmacology*
  • Analgesics / therapeutic use
  • Animals
  • Disulfides / adverse effects
  • Disulfides / pharmacology
  • Disulfides / therapeutic use
  • Down-Regulation / drug effects
  • Drug Design
  • Drugs, Investigational / adverse effects
  • Drugs, Investigational / pharmacology
  • Drugs, Investigational / therapeutic use
  • Humans
  • Models, Biological
  • Opioid Peptides / metabolism*
  • Propylamines / adverse effects
  • Propylamines / pharmacology
  • Propylamines / therapeutic use
  • Protein Processing, Post-Translational / drug effects
  • Proteolysis / drug effects*

Substances

  • 1-(2-((1-ethoxycarbonyloxyethoxycarbonylmethyl)carbamoyl)-3-phenylpropyldisulfanylmethyl)-3-methylsulfanylpropylamine
  • Analgesics
  • Disulfides
  • Drugs, Investigational
  • Opioid Peptides
  • Propylamines