Antisaccades as a follow-up tool in major depressive disorder therapies: a pilot study

Jennifer Malsert; Nathalie Guyader; Alan Chauvin; Mircea Polosan; Emmanuel Poulet; David Szekely; Thierry Bougerol; Christian Marendaz

doi:10.1016/j.psychres.2012.05.007

Antisaccades as a follow-up tool in major depressive disorder therapies: a pilot study

Psychiatry Res. 2012 Dec 30;200(2-3):1051-3. doi: 10.1016/j.psychres.2012.05.007. Epub 2012 May 28.

Authors

Jennifer Malsert¹, Nathalie Guyader, Alan Chauvin, Mircea Polosan, Emmanuel Poulet, David Szekely, Thierry Bougerol, Christian Marendaz

Affiliation

¹ Psychology and NeuroCognition Laboratory (LPNC, CNRS, UMR 5105), Grenoble, France. [email protected]

PMID: 22648007
DOI: 10.1016/j.psychres.2012.05.007

Abstract

Eight patients with major depression, included in a double-blind study, performed an antisaccade task. Results suggested a link between antisaccade performances and clinical scale scores in patients who respond to therapy. Moreover, error rates may well predict response from day of inclusion, thus serving as a state-marker for mood disorders.

MeSH terms

Adult
Aged
Antidepressive Agents / therapeutic use*
Depressive Disorder, Major / drug therapy
Depressive Disorder, Major / physiopathology*
Depressive Disorder, Major / therapy*
Depressive Disorder, Treatment-Resistant / drug therapy*
Depressive Disorder, Treatment-Resistant / physiopathology*
Double-Blind Method
Female
Follow-Up Studies
Humans
Male
Middle Aged
Pilot Projects
Saccades / physiology*
Treatment Outcome

Substances

Antidepressive Agents