Many types of spinal abnormalities can have an impact on an athlete’s ability to participate in sports. One of the challenges in the current era is distinguishing the clinically relevant lesions from the incidental. Almost without exception, a Chiarimal formation, significant syringomyelia or other cyst compressing the spinal cord or nerve roots, tethered spinal cord, or spinal tumor should prompt referral to a neurosurgeon. However, tonsillar ectopia (descent of the cerebellum less than 5 mm beyond the foramen magnum) and small dilatations of the central canal, are very commonly seen and appear to represent normal anatomic variants that place athletes at no increased risk of spinal injury, and should not be considered a contraindication to play. The recommendations made in this article are largely based on consensus and experience, but as we gain more clinical experience to correlate with the increasingly sophisticated imaging findings, we hope that these recommendations can be refined further.