Surgery with vascular reconstruction for soft-tissue sarcomas in the inguinal region: oncologic and functional outcomes

Ann Vasc Surg. 2012 Jul;26(5):693-9. doi: 10.1016/j.avsg.2011.12.003.

Abstract

Background: Treatment of soft-tissue sarcomas involving the inguinal region remains challenging because of difficulties in achieving wide surgical margins due to anatomical features. The study aimed to analyze the oncologic and functional outcomes of wide resection with vascular reconstruction for inguinal soft-tissue sarcomas.

Methods: Three men and seven women were treated for inguinal soft-tissue sarcomas by wide surgical resection with vascular reconstruction.

Results: Arteries and veins were replaced in nine patients, and artery replacement alone was carried out in one patient. Femoral nerve resections were performed in six patients. One patient and five patients developed local recurrence and distant metastases, respectively. Limb salvage was achieved in 9 of 10 patients (90%). Six patients and one patient developed vascular (arterial graft occlusion [n = 1], lymphedema [n = 5]) and nonvascular (hematoma [n = 1]) complications, respectively. Five-year arterial primary patency was 77%. Five-year disease-free and overall survival rates were 45% and 77%, respectively. Functional outcome scores at latest follow-up averaged 87.5% for Musculoskeletal Tumor Society 1993.

Conclusions: En-bloc resection of major critical structures along with tumor and vascular reconstructions using synthetic grafts is a feasible option in limb salvage surgery for inguinal soft-tissue sarcomas.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Amputation, Surgical
  • Blood Vessel Prosthesis Implantation* / adverse effects
  • Blood Vessel Prosthesis Implantation* / mortality
  • Child
  • Disease-Free Survival
  • Female
  • Femoral Artery / pathology
  • Femoral Artery / surgery
  • Femoral Vein / pathology
  • Femoral Vein / surgery
  • Humans
  • Iliac Artery / pathology
  • Iliac Artery / surgery
  • Iliac Vein / pathology
  • Iliac Vein / surgery
  • Japan
  • Kaplan-Meier Estimate
  • Limb Salvage
  • Lower Extremity / blood supply*
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local
  • Plastic Surgery Procedures* / adverse effects
  • Plastic Surgery Procedures* / mortality
  • Reoperation
  • Sarcoma / mortality
  • Sarcoma / secondary
  • Sarcoma / surgery*
  • Soft Tissue Neoplasms / mortality
  • Soft Tissue Neoplasms / pathology
  • Soft Tissue Neoplasms / surgery*
  • Time Factors
  • Treatment Outcome
  • Vascular Patency
  • Young Adult