The secrets of the bone marrow niche: Metabolic priming for AML

Nat Med. 2012 Jun 6;18(6):865-867. doi: 10.1038/nm.2831.
No abstract available

MeSH terms

  • Humans
  • Isocitrate Dehydrogenase / genetics
  • Leukemia, Myeloid, Acute / etiology
  • Leukemia, Myeloid, Acute / metabolism*
  • Myelodysplastic Syndromes / etiology
  • Myelodysplastic Syndromes / metabolism
  • Tumor Microenvironment*

Substances

  • IDH2 protein, human
  • Isocitrate Dehydrogenase
  • IDH1 protein, human