How to regulate a gene: to repress or to activate?

Mol Cell. 2012 Jun 8;46(5):551-2. doi: 10.1016/j.molcel.2012.05.035.

Abstract

Gene-expression responses to an input can depend on growth conditions; in this issue, Sasson et al. (2012) show that this dependence is lower when the input results in a high degree of promoter occupancy.

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