Abstract
Factor VII deficiency (FVIId) is a congenital coagulation disorder with a wide spectrum of bleeding phenotypes. Percutaneous coronary intervention requires full anticoagulation during stent implantation to avoid acute coronary thrombosis and long-term dual antiplatelet therapy. Feasibility of percutaneous coronary intervention in FVIId is not described in literature. We present a successful case of percutaneous coronary intervention in a 55-year-old male with FVIId, discussing briefly the periprocedural handicaps (anticoagulation regimen and hemostasis at arterial puncture site) as the safety of long-term antiplatelet therapy, and future implications for recombinant FVIId administration in a patient with a previous coronary stent.
MeSH terms
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Angina Pectoris / complications
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Angina Pectoris / diagnostic imaging
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Angioplasty, Balloon, Coronary / methods*
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Aspirin / administration & dosage
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Clopidogrel
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Coronary Stenosis / complications
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Coronary Stenosis / diagnostic imaging
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Coronary Stenosis / therapy*
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Diabetes Mellitus, Type 2 / complications
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Diabetes Mellitus, Type 2 / diagnosis
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Factor VII Deficiency / complications
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Factor VII Deficiency / diagnosis*
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Factor VII Deficiency / drug therapy
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Follow-Up Studies
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Humans
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Male
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Middle Aged
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Obesity, Morbid / complications
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Obesity, Morbid / diagnosis
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Platelet Aggregation Inhibitors / administration & dosage*
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Radiography
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Risk Assessment
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Stents*
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Thromboembolism / prevention & control
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Ticlopidine / administration & dosage
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Ticlopidine / analogs & derivatives
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Time Factors
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Treatment Outcome
Substances
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Platelet Aggregation Inhibitors
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Clopidogrel
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Ticlopidine
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Aspirin