Use of Sorafenib as an effective treatment in an AML patient carrying a new point mutation affecting the Juxtamembrane domain of FLT3

MeSH terms

• Aged
• Amino Acid Sequence
• Animals
• Antineoplastic Agents / therapeutic use*
• Benzenesulfonates / therapeutic use*
• Humans
• Leukemia, Myeloid, Acute / drug therapy*
• Male
• Molecular Sequence Data
• Niacinamide / analogs & derivatives
• Phenylurea Compounds
• Point Mutation*
• Pyridines / therapeutic use*
• Sequence Alignment
• Sorafenib
• fms-Like Tyrosine Kinase 3 / genetics*