A case of diaphragmatic paralysis complicated by herpes-zoster virus infection

Intern Med. 2012;51(10):1259-63. doi: 10.2169/internalmedicine.51.6935. Epub 2012 May 15.

Abstract

Diaphragmatic paralysis is commonly caused by surgical and traumatic injuries, malignant neoplasm, and neurodegenerative disorders. However, in rare instances, diaphragmatic paralysis due to herpes-zoster virus infection has been reported. Here, we describe an 85-year-old woman who developed left hemidiaphragmatic paralysis within 19 days of the appearance of a typical herpes-zoster rash involving the C4-5 dermatome on the left side. Clinical and radiological findings revealed no local causes of phrenic nerve lesion. The hemidiaphragmatic paralysis was thought to be caused by herpes-zoster virus infection.

Publication types

  • Case Reports
  • Review

MeSH terms

  • 2-Aminopurine / administration & dosage
  • 2-Aminopurine / analogs & derivatives
  • Aged
  • Aged, 80 and over
  • Antiviral Agents / administration & dosage
  • Famciclovir
  • Female
  • Herpes Zoster / complications*
  • Herpes Zoster / drug therapy
  • Herpes Zoster / physiopathology
  • Humans
  • Phrenic Nerve / physiopathology
  • Respiratory Paralysis / etiology*
  • Respiratory Paralysis / physiopathology
  • Time Factors

Substances

  • Antiviral Agents
  • 2-Aminopurine
  • Famciclovir