Outbreak-associated Vibrio cholerae genotypes with identical pulsotypes, Malaysia, 2009

Emerg Infect Dis. 2012 Jul;18(7):1177-9. doi: 10.3201/eid1807.111656.

Abstract

A cholera outbreak in Terengganu, Malaysia, in November 2009 was caused by 2 El Tor Vibrio cholerae variants resistant to typical antimicrobial drugs. Evidence of replacement of treatable V. cholerae infection in the region with antimicrobial-resistant strains calls for increased surveillance and prevention measures.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Anti-Bacterial Agents / pharmacology
  • Bacterial Typing Techniques
  • Cholera / epidemiology*
  • Cholera / microbiology
  • Cholera Toxin / chemistry
  • Cholera Toxin / genetics*
  • Cholera Toxin / metabolism
  • DNA, Bacterial / genetics
  • Disease Outbreaks*
  • Drug Resistance, Bacterial
  • Environment
  • Genotype
  • Humans
  • Malaysia / epidemiology
  • Microbial Sensitivity Tests
  • Molecular Sequence Data
  • Polymerase Chain Reaction
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Vibrio cholerae / classification*
  • Vibrio cholerae / drug effects
  • Vibrio cholerae / genetics*
  • Vibrio cholerae / isolation & purification
  • Vibrio cholerae O1 / classification*
  • Vibrio cholerae O1 / drug effects
  • Vibrio cholerae O1 / genetics*
  • Vibrio cholerae O1 / isolation & purification

Substances

  • Anti-Bacterial Agents
  • DNA, Bacterial
  • Cholera Toxin