Arterial spin-labeling in routine clinical practice: a preliminary experience of 200 cases and correlation with MRI and clinical findings

Clin Imaging. 2012 Jul-Aug;36(4):345-52. doi: 10.1016/j.clinimag.2011.11.003. Epub 2012 Jun 8.

Abstract

We described our experience with a heterogeneous collection of 200 arterial spin-labeling (ASL) perfusion cases. ASL imaging was performed on a 1.5-T magnetic resonance imaging unit with a receive head coil using a second version of quantitative perfusion imaging. Sixty-four (32%) patients exhibited normal perfusion, 107 (53.5%) patients exhibited hypoperfusion, and 29 (14.5%) exhibited hyperperfusion. This ASL study illustrates the usefulness of ASL perfusion studies in a number of pathological conditions and that perfusion imaging can be implemented successfully in a routine clinical neuroimaging protocol.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Brain Ischemia / diagnosis*
  • Brain Ischemia / pathology
  • Brain Neoplasms / diagnosis*
  • Brain Neoplasms / pathology
  • Cerebrovascular Circulation
  • Cohort Studies
  • Diffusion Magnetic Resonance Imaging / methods*
  • Electron Spin Resonance Spectroscopy / methods*
  • Female
  • Glioblastoma / diagnosis
  • Glioblastoma / pathology
  • Humans
  • Male
  • Middle Aged
  • Neuroimaging / methods
  • Perfusion / methods*
  • Retrospective Studies
  • Sensitivity and Specificity