[Evaluation of the Helicobacter pylori stool antigen test]

Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2011 Dec;25(6):495-6.
[Article in Chinese]

Abstract

Objective: To evaluate the clinical value of an enzyme-linked immunosorbent assay by the Helicobacter pylori stool antigen (HpSA) test for the detection of H. pylori infection.

Methods: 328 patients were measured upper gastrointestinal endoscopic examination which as gold standards and HpSA test in the meantime, comparing accuracy, sensitivity, specificity and other Indicators.

Results: In the diagnosis of Hp infection, HpSA test had no significant difference comparing with gold standards and had a P value of over 0.5. The sensitivity of HpSA test was 94.6%, while the specificity, veracity, expected positive value, and expected negative value were 96.9%, 96.3%, 89.7% and 98.4%, respectively.

Conclusion: The H. pylori stool antigen test is a simple, non-invasive method for accurate diagnosis of H. pylori infection.

Publication types

  • Evaluation Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antigens, Bacterial / analysis*
  • Child
  • Enzyme-Linked Immunosorbent Assay / methods*
  • Feces / microbiology*
  • Female
  • Helicobacter Infections / diagnosis
  • Helicobacter pylori / immunology*
  • Humans
  • Male
  • Middle Aged
  • Sensitivity and Specificity

Substances

  • Antigens, Bacterial