Determining the full three-dimensional orientation of single anisotropic nanoparticles by differential interference contrast microscopy

Angew Chem Int Ed Engl. 2012 Jul 27;51(31):7734-8. doi: 10.1002/anie.201202340. Epub 2012 Jun 26.

Abstract

Keeping track: By combining differential interference contrast (DIC) image pattern recognition with DIC polarization anisotropy, the exact full three-dimensional angular information of individual tilted gold nanorods positioned in the focal plane of the objective lens can be readily determined. The angular rotational modes and kinetics of individual in-focus gold nanorods can thus be resolved dynamically.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Anisotropy
  • Gold / analysis*
  • Metal Nanoparticles / analysis*
  • Microscopy, Phase-Contrast*
  • Particle Size

Substances

  • Gold