Miliary pulmonary tuberculosis following intravesical BCG therapy: case report and literature review

Juan D Colmenero; Rocío Sanjuan-Jimenez; Blanca Ramos; Pilar Morata

doi:10.1016/j.diagmicrobio.2012.05.026

Miliary pulmonary tuberculosis following intravesical BCG therapy: case report and literature review

Diagn Microbiol Infect Dis. 2012 Sep;74(1):70-2. doi: 10.1016/j.diagmicrobio.2012.05.026. Epub 2012 Jun 28.

Authors

Juan D Colmenero¹, Rocío Sanjuan-Jimenez, Blanca Ramos, Pilar Morata

Affiliation

¹ Infectious Diseases Service, Carlos Haya University Hospital, Malaga, 29010, Spain. [email protected]

PMID: 22749242
DOI: 10.1016/j.diagmicrobio.2012.05.026

Abstract

Miliary tuberculosis after intravesical Calmette-Guerin bacilli (BCG) therapy is rare. To date, only 23 cases have been reported. We describe the case of a patient on hemodialysis, review the literature, and call attention to the potential hazard of intravesical BCG therapy in patients on renal replacement therapy and the value of polymerase chain reaction-based methods for early diagnosis of this serious complication.

Publication types

Case Reports
Research Support, Non-U.S. Gov't
Review

MeSH terms

Administration, Intravesical
Biological Therapy / adverse effects*
Biological Therapy / methods*
Humans
Male
Middle Aged
Mycobacterium bovis / isolation & purification*
Radiography, Thoracic
Tomography, X-Ray Computed
Tuberculosis, Miliary / diagnosis*
Tuberculosis, Miliary / pathology
Tuberculosis, Pulmonary / diagnosis*
Tuberculosis, Pulmonary / pathology
Urinary Bladder Neoplasms / therapy*