SAP signaling: a dual mechanism of action

Marie Le Borgne; Andrey S Shaw

doi:10.1016/j.immuni.2012.06.002

SAP signaling: a dual mechanism of action

Immunity. 2012 Jun 29;36(6):899-901. doi: 10.1016/j.immuni.2012.06.002.

Authors

Marie Le Borgne¹, Andrey S Shaw

Affiliation

¹ Department of Pathology and Immunology, Washington University School of Medicine, 660 South Euclid Avenue, Saint Louis, MO 63110, USA.

PMID: 22749348
DOI: 10.1016/j.immuni.2012.06.002

Abstract

In this issue of Immunity, Kageyama et al. (2012), Zhao et al. (2012), and Dong et al. (2012) show that the adaptor protein SAP regulates both positive and negative signals through SLAM receptors to stabilize intercellular contacts.

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