Evaluation of a new molecular test, the BD Max Cdiff, for detection of toxigenic Clostridium difficile in fecal samples

J Clin Microbiol. 2012 Sep;50(9):3089-90. doi: 10.1128/JCM.01250-12. Epub 2012 Jul 3.

Abstract

A new molecular assay detecting toxigenic Clostridium difficile, the BD Max Cdiff (Becton, Dickinson), was evaluated with 360 diarrheal feces samples. It exhibited high sensitivity (97.7%) and specificity (99.7%). The positive (97.7%) and negative (99.7%) predictive values of this test allow an accurate answer within 2 h.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Toxins / metabolism*
  • Bacteriological Techniques / methods*
  • Clostridioides difficile / isolation & purification*
  • Clostridium Infections / diagnosis*
  • Clostridium Infections / microbiology
  • Diarrhea / diagnosis
  • Diarrhea / microbiology
  • Feces / microbiology*
  • Humans
  • Molecular Diagnostic Techniques / methods*
  • Predictive Value of Tests
  • Sensitivity and Specificity
  • Time Factors

Substances

  • Bacterial Toxins