Association study of X chromosome SNPs in attempted suicide

Psychiatry Res. 2012 Dec 30;200(2-3):1044-6. doi: 10.1016/j.psychres.2012.06.001. Epub 2012 Jul 4.

Abstract

We report the results of a high-density attempted suicide association study of the X chromosome, which genotyped 23,141 SNPs on 983 attempters and 1143 non-attempters and generated modest evidence for association for SH3KBP1 (P=1.07×10(-4)) and GRIA3 (P=4.01×10(-4)). These findings highlight the need for larger sample sets and meta-analytic approaches.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Bipolar Disorder / genetics
  • Chromosomes, Human, X / genetics*
  • Female
  • Genetic Association Studies
  • Genotype
  • Humans
  • Male
  • Polymorphism, Single Nucleotide*
  • Psychotic Disorders / genetics
  • Risk Factors
  • Suicide, Attempted*