An adjunct intervention for management of acute exacerbation of chronic obstructive pulmonary disease (AECOPD)

J Altern Complement Med. 2013 Feb;19(2):178-81. doi: 10.1089/acm.2011.0222. Epub 2012 Jul 9.

Abstract

Objectives: Application of transcutaneous electrical nerve stimulation over acupuncture points (Acu-TENS) is a noninvasive intervention that has recently been shown to alleviate dyspnea in patients with stable chronic obstructive pulmonary disease (COPD). This case report aims to explore the role of Acu-TENS in patients diagnosed with COPD during the acute exacerbation.

Study design: The study design was a case report.

Setting: The study was conducted in an inpatient setting.

Subject: The subject was a 74-year-old man admitted to the hospital due to acute exacerbation of COPD (AECOPD).

Intervention: Treatment consisted of application of TENS on EX-B1 (Dingchuan) for 45 minutes.

Outcome measures: Oxygen saturation, heart rate, and dyspnea score were measured before, immediately after, and 45 minutes after Acu-TENS intervention. Other than the physiologic measures, 10 mL of venous blood was taken from the cubital vein for assessment of β-endorphin level, white blood cell count, tumor necrosis factor-α (TNF-α), and C-reactive protein (CRP) level before and immediately postintervention.

Results: Postintervention, improved oxygen saturation, and reduction in heart rate and dyspneic sensation were observed accompanied by a raised blood β-endorphin level but the level of white blood cell count, TNF-α, and CRP remain unchanged.

Conclusions: Application of 45 minutes Acu-TENS appeared to alleviate symptoms in a patient with AECOPD. The role of adjunctive Acu-TENS therapy during acute exacerbation warrants further investigation.

Publication types

  • Case Reports

MeSH terms

  • Acupuncture Points*
  • Acute Disease
  • Aged
  • C-Reactive Protein / metabolism
  • Dyspnea / prevention & control*
  • Heart Rate*
  • Humans
  • Leukocyte Count
  • Male
  • Outcome Assessment, Health Care
  • Oxygen / metabolism*
  • Pulmonary Disease, Chronic Obstructive / blood
  • Pulmonary Disease, Chronic Obstructive / physiopathology
  • Pulmonary Disease, Chronic Obstructive / therapy*
  • Transcutaneous Electric Nerve Stimulation*
  • Tumor Necrosis Factor-alpha / blood
  • beta-Endorphin / blood*

Substances

  • Tumor Necrosis Factor-alpha
  • beta-Endorphin
  • C-Reactive Protein
  • Oxygen