Aseptic meningitis and adult respiratory distress syndrome caused by Borrelia persica

Infection. 2012 Dec;40(6):695-7. doi: 10.1007/s15010-012-0296-8. Epub 2012 Jul 11.

Abstract

Introduction: The occurrence of some of the clinical complications of tickborne relapsing fever varies with Borrelia species. For example, adult respiratory distress syndrome (ARDS), a newly reported complication, was described so far only with B. hermsii infection.

Materials and methods: A previously healthy young Israeli man was admitted for fever and headache and was diagnosed as aseptic meningitis. Shortly before the lumbar puncture was performed he started to experience shortness of breath and developed acute respiratory insufficiency necessitating mechanical ventilation. Radiography, which was normal on admission, demonstrated bilateral lung infiltrates consistent with ARDS. Spirochetes suggestive of Borrelia were seen on a thick blood smear preparation, and polymerase chain reaction was positive for B. persica.

Conclusion: This is the first reported case of ARDS in association with Borrelia spp. occurring outside the U.S.A. and the first one due to B. persica infection.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Borrelia / genetics
  • Borrelia / isolation & purification*
  • Borrelia Infections / microbiology*
  • Humans
  • Israel
  • Male
  • Meningitis, Aseptic / microbiology*
  • Polymerase Chain Reaction
  • Respiratory Distress Syndrome / microbiology*