[Pharmacological studies on dingchuanning]

Zhongguo Zhong Yao Za Zhi. 1990 Nov;15(11):685-9, 704.
[Article in Chinese]

Abstract

Dingchuanning has been found to increase markedly the perfusion of isolated lung of guinea-pig. It may produce a relaxing effect on the smooth muscles of the isolated trachea, bronchus and lung strips of guinea-pigs, as well as a prominent protective effect on the bronchial asthma induced by inhalation of bronchoconstrictors in conscious guinea-pigs. It also has significant expectorant and antianaphylactic effects and helps to inhibit markedly the SRS-A release from lung tissues and to counteract directly the activity of SRS-A.

MeSH terms

  • Animals
  • Asthma / drug therapy
  • Drug Combinations
  • Drugs, Chinese Herbal / pharmacology*
  • Drugs, Chinese Herbal / therapeutic use
  • Drugs, Chinese Herbal / toxicity
  • Expectorants
  • Female
  • Guinea Pigs
  • Hypoxia / drug therapy
  • In Vitro Techniques
  • Male
  • Mice
  • Muscle Contraction / drug effects*
  • Muscle, Smooth / drug effects
  • Rats
  • Rats, Inbred Strains
  • SRS-A / metabolism
  • Trachea / drug effects

Substances

  • Drug Combinations
  • Drugs, Chinese Herbal
  • Expectorants
  • SRS-A