Abstract
We report on the HLA typing of three brothers (A, B, C) with rheumatoid arthritis (RA) and their six sons. This family is interesting for the full concordance for RA between parents. The aim of this study was the discovery of genetic and/or enviromental cofactors determining this absolute concordance.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Adult
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Aged
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Arthritis, Rheumatoid / etiology
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Arthritis, Rheumatoid / genetics*
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Asbestos
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Environmental Exposure*
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Female
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Genes, MHC Class I
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Genes, MHC Class II
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Genetic Predisposition to Disease
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HLA Antigens / genetics*
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Humans
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Male
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Mixed Connective Tissue Disease / genetics
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Risk Factors
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Sex Factors
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Siblings
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Sjogren's Syndrome / genetics
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Tobacco Smoke Pollution
Substances
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HLA Antigens
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Tobacco Smoke Pollution
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Asbestos