Novel methods and devices to enhance transdermal drug delivery: the importance of laser radiation in transdermal drug delivery

Ther Deliv. 2012 Mar;3(3):373-88. doi: 10.4155/tde.12.10.

Abstract

Skin permeation-enhancement technology is a rapidly developing field, which could significantly increase the number of drugs suitable for transdermal delivery. In this review, we highlight recent advances in both 'passive' and 'active' transdermal drug-delivery technologies, as well as in the laser ablation method. This paper concludes with a brief forward-looking perspective discussing what can be expected as laser technology continues to develop in the coming years.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Administration, Cutaneous*
  • Drug Delivery Systems / instrumentation*
  • Drug Delivery Systems / methods*
  • Humans
  • Iontophoresis
  • Lasers*
  • Liposomes
  • Needles
  • Skin Absorption

Substances

  • Liposomes