Abstract
Cancer stem cells (CSCs) may be responsible for tumor recurrence. Metabolic labelling of newly synthesized proteins with non-canonical amino acids allows us to discriminate CSCs in mixed populations due to the quiescent nature of these cells.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkynes / metabolism*
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Cell Separation / methods*
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Colonic Neoplasms / pathology*
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Glycine / analogs & derivatives*
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Glycine / metabolism
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HCT116 Cells
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Humans
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Neoplastic Stem Cells / metabolism
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Neoplastic Stem Cells / pathology*
Substances
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Alkynes
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homopropargylglycine
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Glycine