Abstract
Putative animal reservoirs and environmental samples were studied to investigate potential routes of transmission for indigenous hepatitis E virus (HEV) infection in Hokkaido, Japan. A total of 468 liver samples and 954 environmental samples were collected from 2003 to 2011 for this study. Four swine livers (1 %) were positive for HEV RNA; two strains belonged to genotype 3 and the other two strains were genotype 4. Genotype 3 HEV was detected in a sewage sample and a seawater sample. HEV strains derived from swine liver, seawater and raw sewage samples shared 93-100 % sequence similarity with human HEV strains.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Base Sequence
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Deer
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Disease Reservoirs / virology
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Food Microbiology
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Genetic Variation*
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Genotype
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Hepatitis E / epidemiology
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Hepatitis E / veterinary*
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Hepatitis E / virology
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Hepatitis E virus / classification
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Hepatitis E virus / genetics*
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Humans
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Japan / epidemiology
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Liver / virology
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Molecular Sequence Data
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Norgestrel / analogs & derivatives
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Ostreidae / virology
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Phylogeny
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RNA, Viral / isolation & purification
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Rivers / virology
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Seawater / virology
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Sewage / virology
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Swine
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Swine Diseases / epidemiology
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Swine Diseases / virology*
Substances
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3,17-diethynyl-13-ethyl-3,5-gonadiene-17-ol
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RNA, Viral
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Sewage
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Norgestrel
Associated data
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GENBANK/AB679634
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GENBANK/AB679635
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GENBANK/AB679636
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GENBANK/AB679637
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GENBANK/AB679638
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GENBANK/AB682756
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GENBANK/AB683157
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GENBANK/AB683158
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GENBANK/AB683159
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GENBANK/AB683160
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GENBANK/AB683161
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GENBANK/AB683162
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GENBANK/AB683163
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GENBANK/AB683164
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GENBANK/AB683165
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GENBANK/AB683166
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GENBANK/AB683167
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GENBANK/AB683168
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GENBANK/AB683169
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GENBANK/AB683170
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GENBANK/AB683171
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GENBANK/AB683172
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GENBANK/AB683173
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GENBANK/AB683174
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GENBANK/AB683175
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GENBANK/AB683176
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GENBANK/AB683177
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GENBANK/AB683178
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GENBANK/AB683179
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GENBANK/AB683180
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GENBANK/AB683181
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GENBANK/AB683182
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GENBANK/AB683183
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GENBANK/AB683184
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GENBANK/AB683185
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GENBANK/AB683186
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GENBANK/AB721083
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GENBANK/AB721084
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GENBANK/AB721085
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GENBANK/AB721086